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Streptozotocin-induced diabetes, bile-pancreatic secretion and insulo-pancreon-axis interaction / Streptozotocin-induced diabetes, bile-pancreatic secretion and insulo-pancreon-axis interaction.
Tiscornia Osvaldo Manuel; Rodríguez Ricardo Raúl; Sussemil Carlota; Otero Graciela; Negri Gustavo Alberto; Waisman Hipólito; López Mingorance Fabiana Norma; Tiscornia Wasserman Patricia Graciela.
Afiliação
  • Tiscornia Osvaldo Manuel; s.af
  • Rodríguez Ricardo Raúl; s.af
  • Sussemil Carlota; s.af
  • Otero Graciela; s.af
  • Negri Gustavo Alberto; s.af
  • Waisman Hipólito; s.af
  • López Mingorance Fabiana Norma; s.af
  • Tiscornia Wasserman Patricia Graciela; s.af
Acta gastroenterol. latinoam ; Acta gastroenterol. latinoam;43(4): 294-300, 2013 Dec.
Article em Es | LILACS, BINACIS | ID: biblio-1157399
Biblioteca responsável: AR5.1
Localização: [{"text": "AR5.1"}]
ABSTRACT
The present tests were undertaken in order to analyze in male Wistar rats the changes in the exocrine and endocrine pancreas and on the interactions that normally evolve in the insulo-pancreon-axis. To evaluate this by a single i.p. Boots secretin injection, glycemia (G), amylasemia (A) and lipasemia (L) were determined. In bile-pancreatic secretion, we analyzed, pre and post-secretin, the following parameters volume (V), bicarbonate output (BO), amylase output (AO) and lipase output (LO). Three groups of tests were done a) control (C); b) streptozotocin-treated non-diabetic-rats (St-ND) and c) streptozotocin-treated diabetic animals (St-D) which showed morning glycemia values higher than 16.0 mmol/l. Four months later, under Tiopental i.p anesthesia, a bile-pancreatic fistula was done. Following a 30 min basal period, Boots secretin (20 CU/kg) was i.p injected. Bile-pancreatic secretion put in evidence a significant fall of BO in both St-ND and St-D series. In controls, AO revealed a post-secretin increase of 160
Assuntos
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Coleções: 01-internacional Base de dados: BINACIS / LILACS Assunto principal: Pâncreas / Bile / Diabetes Mellitus Experimental Idioma: Es Revista: Acta gastroenterol. latinoam Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2013 Tipo de documento: Article País de publicação: Argentina
Buscar no Google
Coleções: 01-internacional Base de dados: BINACIS / LILACS Assunto principal: Pâncreas / Bile / Diabetes Mellitus Experimental Idioma: Es Revista: Acta gastroenterol. latinoam Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2013 Tipo de documento: Article País de publicação: Argentina