AIDS-related progressive multifocal leukoencephalopathy
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;54: e02522020, 2021. tab
Article
em En
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1143893
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).METHODS:
We described the profile of laboratory-confirmed PML cases among AIDS patients.RESULTS:
A total of 43 HIV patients with clinical conditions compatible with PML were obtained; 5 cases were confirmed by JCV testing. The main clinical finding was mental confusion. Median CD4 count was 54 cells/mm³.CONCLUSIONS:
Three of the five confirmed PML cases died; the time between diagnosis and death was 2, 5, and 6 months. It is important to consider JCV infection as a differential diagnosis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
/
SES-SP
/
ColecionaSUS
Assunto principal:
Infecções por HIV
/
Síndrome da Imunodeficiência Adquirida
/
Leucoencefalopatia Multifocal Progressiva
/
Vírus JC
Limite:
Humans
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
MEDICINA TROPICAL
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil