Antibacterial activity of Cinnamomum cassia L. essential oil in a carbapenem- and polymyxin-resistant Klebsiella aerogenes strain
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;53: e20200032, 2020. tab, graf
Article
em En
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136877
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Essential oils can serve as novel sources of antibiotics for multidrug-resistant bacteria.METHODS:
The multidrug-resistance profile of a Klebsiella aerogenes strain was assessed by PCR and sequencing. The antibacterial activity of Cinnamomum cassia essential oil (CCeo) against K. aerogenes was assessed by broth microdilution and time-kill methods.RESULTS:
K. aerogenes showed high antibiotic resistance. The genes bla KPC-2, ampC, bla CTX-M-15, bla OXA-1, and bla TEM were present. CCeo exhibited an inhibitory effect with a minimum inhibitory concentration of 17.57 μg/mL.CONCLUSIONS:
The antibacterial activity of CCeo makes it a potential candidate for treating carbapenem- and polymyxin-resistant K. aerogenes strains.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
/
SES-SP
/
ColecionaSUS
Assunto principal:
Infecções por Klebsiella
/
Enterobacter aerogenes
/
Cinnamomum aromaticum
/
Antibacterianos
Limite:
Humans
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
MEDICINA TROPICAL
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil