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Spindle cell carcinoma of the maxillary sinus with extension to the oral cavity
Donohue-Cornejo, Alejandro; Almeida, Oslei Paes de; Sánchez-Romero, Celeste; Bologna-Molina, Ronell; Espinosa-Cristóbal, León Francisco; Cuevas González, Juan Carlos.
Afiliação
  • Donohue-Cornejo, Alejandro; Autonomous University of Ciudad Juárez. Biomedical Sciences Institute. Stomatology Department. Ciudad Juárez. MX
  • Almeida, Oslei Paes de; State University of Campinas. Dentistry Faculty of Piracicaba. Diagnosis Department. Piracicaba. BR
  • Sánchez-Romero, Celeste; University of the Republic. Faculty of Dentistry. Molecular Pathology Area. Montevideo. UY
  • Bologna-Molina, Ronell; University of the Republic. Faculty of Dentistry. Molecular Pathology Area. Montevideo. UY
  • Espinosa-Cristóbal, León Francisco; Autonomous University of Ciudad Juárez. Biomedical Sciences Institute. Stomatology Department. Ciudad Juárez. MX
  • Cuevas González, Juan Carlos; Autonomous University of Ciudad Juárez. Biomedical Sciences Institute. Stomatology Department. Ciudad Juárez. MX
Autops. Case Rep ; 10(3): e2020161, 2020. tab, graf
Article em En | BNUY-Odon, LILACS, BNUY | ID: biblio-1131825
Biblioteca responsável: BR26.7
ABSTRACT
Spindle cell carcinoma (SCC) is a rare variant of squamous cell carcinoma characterized by elongated and pleomorphic epithelial cells that resemble a sarcoma. Due to its rareness, and histological resemblance to various sarcomas, the diagnosis of this neoplasia is challenging. Herein we present the case of an 82-year-old female with a polypoid, ulcerated, soft tissue mass located on the left side of the maxilla. The tomographic examination showed a hyperdense mass that infiltrated the orbital cavity, ethmoidal cells, middle and lower nasal concha, maxillary sinus, zygomatic arch, and mandibular ramus on the left side. Histopathologically, the tumor was composed of spindle cells that were sarcomatous in appearance, with aberrant mitosis, along with a group of pleomorphic cells with a more epithelioid and hyperchromatic appearance on a stroma of densely vascularized fibrous tissue. The immunohistochemistry panel used to determine the lineage of the tumor rendered the diagnosis of SCC. The diagnosis of SCC is challenging to the pathologist since its morphology can resemble a sarcoma. Thus, immunohistochemistry is a valuable resource to support the diagnosis. We propose that SCC should be considered when examining a biphasic neoplasm with the aforementioned histological characteristics and markers.
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Texto completo: 1 Coleções: 01-internacional Base de dados: BNUY / BNUY-Odon / LILACS Assunto principal: Carcinoma / Carcinoma de Células Escamosas / Maxila / Boca Limite: Aged / Aged80 / Female / Humans Idioma: En Revista: Autops. Case Rep Assunto da revista: Anatomia / Patologia Cl¡nica / Patologia Legal Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil / México / Uruguai País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: BNUY / BNUY-Odon / LILACS Assunto principal: Carcinoma / Carcinoma de Células Escamosas / Maxila / Boca Limite: Aged / Aged80 / Female / Humans Idioma: En Revista: Autops. Case Rep Assunto da revista: Anatomia / Patologia Cl¡nica / Patologia Legal Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil / México / Uruguai País de publicação: Brasil