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Enterovirus 71 infection and acute neurological disease among children in Brazil (1988-1990)
Takimoto, Sueko; Waldman, Eliseu Alves; Moreira, Regina Celia; Kok, Fernando; Pinheiro, Francisco de Paula; Saes, Sueli Gonsales; Hatch, Milford; Souza, Denise Ferreira Correa de; Carmona, Rita de Cassia Compagnoli; Shout, Denise; Moraes, José Cassio de; Costa, Ady Maria.
Afiliação
  • Takimoto, Sueko; Instituto Adolfo Lutz. Department of Virology. São Paulo. BR
  • Waldman, Eliseu Alves; University of São Paulo. School of Public Health. Department of Epidemiology. São Paulo. BR
  • Moreira, Regina Celia; Instituto Adolfo Lutz. Department of Virology. São Paulo. BR
  • Kok, Fernando; University of São Paulo. School of Medicine. Department of Neurology. São Paulo. BR
  • Pinheiro, Francisco de Paula; Panamerican Health Organization. Washington. US
  • Saes, Sueli Gonsales; Instituto Adolfo Lutz. Department of Virology. São Paulo. BR
  • Hatch, Milford; Panamerican Health Organization. Washington. US
  • Souza, Denise Ferreira Correa de; Instituto Adolfo Lutz. Department of Virology. São Paulo. BR
  • Carmona, Rita de Cassia Compagnoli; Instituto Adolfo Lutz. Department of Virology. São Paulo. BR
  • Shout, Denise; São Paulo(State) Health Department. Epidemiological Surveillance Centre. São Paulo. BR
  • Moraes, José Cassio de; São Paulo(State) Health Department. Epidemiological Surveillance Centre. São Paulo. BR
  • Costa, Ady Maria; Public Health Department. Brasília, DF. BR
Trans R Soc Trop Med Hyg ; 92(1): 25-28, jan.-fev. 1998. tab, graf
Article em En | SES-SP, SESSP-CTDPROD, SES-SP, SESSP-ACVSES, SESSP-CVEPROD, SES-SP, SESSP-IALPROD, SES-SP, SESSP-IALACERVO | ID: biblio-1068292
Biblioteca responsável: BR91.2
Localização: BR91.2; P / BR76.1; P
ABSTRACT
Surveillance for Enterovirus 71 (EV-71) infection in children up to 15 years of age was carried out in Brazil, from 1988 to 1990. Patients with acute neurological diseases (AND) such as flaccid paralysis, Bell's palsy, acute cerebellar ataxia and Guillain-Barré syndrome were included in the study. EV-71 infection was detected in 24 of 426 children (5.6%) with AND. EV-71 infection was confirmed only by virus isolation in 13 children, by virus isolation and seroconversion in 4, and by seroconversion alone in 7. EV-71 was also isolated from 15 of the 427 household contacts (3.5%) of 165 AND patients. There was some evidence of high infectivity of EV-71 household clusters were detected in the case of 7 of 24 children (29.1%) infected with EV-71 and manifesting AND; EV-71 was isolated from 11/40 household contacts (27.5%) of the infected patients but from only 4/387 household contacts (1.0%) of children in whom it was not possible to demonstrate EV-71 infection. Seven of the 24 children infected with EV-71 exhibited residual motor deficiency when examined 6 months after the disease onset. The relevance of these results for the Plan for Global Eradication of Wild Poliovirus is discussed, as well as the need to increase knowledge about the behaviour of this virus and its possible association with AND
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Coleções: 06-national / BR Base de dados: SES-SP / SESSP-ACVSES / SESSP-CTDPROD / SESSP-CVEPROD / SESSP-IALACERVO / SESSP-IALPROD Assunto principal: Poliomielite / Epidemiologia / Enterovirus Humano A Limite: Child / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Trans R Soc Trop Med Hyg Ano de publicação: 1998 Tipo de documento: Article
Buscar no Google
Adicionar na Minha BVS
Imprimir
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Coleções: 06-national / BR Base de dados: SES-SP / SESSP-ACVSES / SESSP-CTDPROD / SESSP-CVEPROD / SESSP-IALACERVO / SESSP-IALPROD Assunto principal: Poliomielite / Epidemiologia / Enterovirus Humano A Limite: Child / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Trans R Soc Trop Med Hyg Ano de publicação: 1998 Tipo de documento: Article