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Transesophageal echocardiography improves risk assessment of thrombolysis prosthetic valve thrombosis: results of the international PRO-TEE registry
Tong, Ann T; Roudaut, Raymond; Ozkan, Mehmet; Sagie, Alex; Shahid, Maie S A; Pontes Junior, Sergio C; Carreras, Francesc; Girard, Steven E; Arnaout, Samir; Stainback, Raymond F; Thadhani, Ravi; Zoghbi, William A.
Afiliação
  • Tong, Ann T; Bayllor College of Medicine. US
  • Roudaut, Raymond; Hospital Cardiologique Du Haut Leveque. FR
  • Ozkan, Mehmet; Kosuyolo heart ans Research Hospital. TR
  • Sagie, Alex; Rabin Medical Center. IL
  • Shahid, Maie S A; King Faisel Specialists Hospital and Research Center. SA
  • Pontes Junior, Sergio C; instituto Dante Pazzanese de Cardiologia. BR
  • Carreras, Francesc; Hospital De La Sant Creu I Sant Paul. ES
  • Girard, Steven E; Mayo Clinic. US
  • Arnaout, Samir; American University of Beirut. LB
  • Stainback, Raymond F; Texas Heart Institute. US
  • Thadhani, Ravi; Massachusetts General Hospital. US
  • Zoghbi, William A; Bayllor College of Medicine. US
J. Am. Coll. Cardiol ; J. Am. Coll. Cardiol;43(1): 77-784, 07012004. ilus
Article em En | SES-SP, SESSP-IDPCPROD, SES-SP | ID: biblio-1063723
Biblioteca responsável: BR79.1
Localização: BR79.1
ABSTRACT
The goal of this study was to evaluate whether antitation of thrombus burden with transesophageal echocardiography (TEE) can help risk-stratify patients undergoing thrombolysis of prosthetic valve thrombosis (PVT).

BACKGROUND:

Thrombolytic therapy of PVT has an unpredictable risk of embolization and complications.

METHODS:

An international registry of patients with suspected PVT undergoing two-dimensional/Doppler and TEE before thrombolysis was established. All TEE studies were reviewed and quantitated by a single observer blinded to all data.

RESULTS:

From 1985 to 2001, 107 patients (71 females; age 24 to 86 years) from 14 centers (6 in the U.S.) were identified. The majority of cases involved the mitral valve (79 mitral, 13 aortic, and 15 tricuspid). Hemodynamic success rate was achieved in 85% and was similar across valves. Overall complications were observed in 17.8%, and death in 5.6%.Predictors of complications were New York Heart Association (NYHA) functional class, presence of shock, sinus tachycardia, hypotension,previous history of stroke, thrombus extension beyond the valve ring, and thrombus area. Multivariate analysis demonstrated that two variables were independent predictors of complications thrombus area by TEE (odds ratio [OR] 2.41 per 1 cm2 increment, 95% confidence interval [CI] 1.12 to 5.19)and prior history of stroke (OR 4.55, 95% CI 1.35 to 15.38). A thrombus area <0.8 cm2 identified patients at lower risk for complications from thrombolysis, irrespective of NYHA functional class...
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Coleções: 06-national / BR Base de dados: SES-SP / SESSP-IDPCPROD Assunto principal: Trombose / Próteses Valvulares Cardíacas / Ecocardiografia / Terapia Trombolítica Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male Idioma: En Revista: J. Am. Coll. Cardiol Ano de publicação: 2004 Tipo de documento: Article
Buscar no Google
Adicionar na Minha BVS
Imprimir
XML
Coleções: 06-national / BR Base de dados: SES-SP / SESSP-IDPCPROD Assunto principal: Trombose / Próteses Valvulares Cardíacas / Ecocardiografia / Terapia Trombolítica Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male Idioma: En Revista: J. Am. Coll. Cardiol Ano de publicação: 2004 Tipo de documento: Article