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The use of circulating cathodic antigen rapid test and serology for diagnosis of active Schistosoma mansoni infection in migrants in Italy, a non-endemic country: a cross sectional study
Infurnari, Laura; Galli, Laura; Bigoloni, Alba; Carbone, Alessia; Chiappetta, Stefania; Sala, Angelo; Ceserani, Norberto; Lazzarin, Adriano; Castagna, Antonella; Gaiera/, Giovanni.
Afiliação
  • Infurnari, Laura; San Raffaele Scientific Institute. Laboratory of Microbiology and Virology. Milan. IT
  • Galli, Laura; San Raffaele Scientific Institute. Infectious Diseases Department. Milan. IT
  • Bigoloni, Alba; San Raffaele Scientific Institute. Infectious Diseases Department. Milan. IT
  • Carbone, Alessia; San Raffaele Scientific Institute. Infectious Diseases Department. Milan. IT
  • Chiappetta, Stefania; San Raffaele Scientific Institute. Infectious Diseases Department. Milan. IT
  • Sala, Angelo; Society of Priests of the Sacred Heart of Betharram. Bouar. CF
  • Ceserani, Norberto; San Raffaele Scientific Institute. Infectious Diseases Department. Milan. IT
  • Lazzarin, Adriano; San Raffaele Scientific Institute. Infectious Diseases Department. Milan. IT
  • Castagna, Antonella; San Raffaele Scientific Institute. Infectious Diseases Department. Milan. IT
  • Gaiera/, Giovanni; San Raffaele Scientific Institute. Infectious Diseases Department. Milan. IT
Mem. Inst. Oswaldo Cruz ; 112(6): 452-455, June 2017. tab
Article em En | LILACS | ID: biblio-1040569
Biblioteca responsável: BR1.1
ABSTRACT
ABSTRACT Diagnosis of schistosomiasis in migrants coming from endemic areas can be difficult, especially in asymptomatic subjects. Light-intensity disease, in fact, may be missed due to the low sensitivity of the stool microscopy and serologic testing cannot distinguish between a resolved infection and an active infection in patients who have been infected and treated in the past, because specific antibodies can persist despite cure. We describe a cross-sectional study conducted on 82 migrants tested for Schistosoma mansoni on single blood (anti-schistosome antibodies, total IgE) and urine [point-of-care (POC) circulating-cathodic-antigen (CCA) test] samples. A positive POC-CCA test (active infection) resulted in two untreated patients with a positive serology while all patients (n = 66) with a past infection showed a negative POC-CCA test. POC-CCA urine test in combination with serology may be helpful in rapidly differentiate active from past S. mansoni infection in migrants coming from endemic areas.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Schistosoma mansoni / Migrantes / Esquistossomose mansoni / Antígenos de Helmintos Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male País/Região como assunto: Europa Idioma: En Revista: Mem. Inst. Oswaldo Cruz Assunto da revista: MEDICINA TROPICAL / PARASITOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: República Centro-Africana / Itália País de publicação: Brasil
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Schistosoma mansoni / Migrantes / Esquistossomose mansoni / Antígenos de Helmintos Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male País/Região como assunto: Europa Idioma: En Revista: Mem. Inst. Oswaldo Cruz Assunto da revista: MEDICINA TROPICAL / PARASITOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: República Centro-Africana / Itália País de publicação: Brasil