Comparative study of four different types of intraperitoneal mesh prostheses in rats
Acta cir. bras
; Acta cir. bras;34(7): e201900703, 2019. tab, graf
Article
em En
| LILACS
| ID: biblio-1038114
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Purpose:
To compare four types of mesh regarding visceral adhesions, inflammatory response and incorporation.Methods:
Sixty Wistar rats were divided into four groups, with different meshes implanted intraperitoneally polytetrafluoroethylene (ePTFE group); polypropylene with polydioxanone and oxidized cellulose (PCD); polypropylene (PM) and polypropylene with silicone (PMS). The variables analyzed were area covered by adhesions, incorporation of the mesh and inflammatory reaction (evaluated histologically and by COX2 immunochemistry).Results:
The PMS group had the lowest adhesion area (63.1%) and grade 1 adhesions. The ePTFE and PM groups presented almost the total area of their surface covered by adherences (99.8% and 97.7% respectively) The group ePTFE had the highest percentage of area without incorporation (42%; p <0.001) with no difference between the other meshes. The PMS group had the best incorporation rate. And the histological analysis revealed that the inflammation scores were significantly different.Conclusions:
The PM mesh had higher density of adherences, larger area of adherences, adherences to organs and percentage of incorporation. ePTFE had the higher area of adherences and lower incorporation. The PMS mesh performed best in the inflammation score, had a higher incorporation and lower area of adherences, and it was considered the best type of mesh.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Próteses e Implantes
/
Telas Cirúrgicas
/
Aderências Teciduais
/
Hérnia Incisional
/
Inflamação
Limite:
Animals
Idioma:
En
Revista:
Acta cir. bras
Assunto da revista:
Cirurgia Geral
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil