Identification of Tiletamine, Zolazepam and Their Metabolites in Drug Facilitated Sexual Assault by GC-QTOF-MS / 法医学杂志
Journal of Forensic Medicine
; (6): 581-585, 2019.
Article
en En
| WPRIM
| ID: wpr-985050
Biblioteca responsable:
WPRO
ABSTRACT
Objective To identify tiletamine, zolazepam and their metabolites in samples from drug facilitated sexual assault by gas chromatography-quadrupole time of flight mass spectrometry （GC-QTOF-MS）. Methods Urine samples of victims were collected, and detected by GC-QTOF-MS after liquid-liquid extraction and concentration. The molecular formula of fragments ions was identified by determination of accurate mass numbers, to detect related substances. Results Tiletamine, zolazepam, three metabolites of tiletamine and two metabolites of zolazepam were identified in urine samples from actual cases. Conclusion GC-QTOF-MS provides abundant and accurate information of fragment ions mass numbers, which can be used for qualitative identification of tiletamine, zolazepam and their metabolites in drug facilitated sexual assault.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Delitos Sexuales
/
Tiletamina
/
Zolazepam
/
Cromatografía Líquida de Alta Presión
/
Espectrometría de Masas en Tándem
/
Toxicología Forense
/
Cromatografía de Gases y Espectrometría de Masas
Límite:
Humans
Idioma:
En
Revista:
Journal of Forensic Medicine
Año:
2019
Tipo del documento:
Article