The diagnostic accuracy of SARS-CoV-2 rapid antibody tests among asymptomatic employees returning to work during General Community Quarantine Period (June 1 to July 31, 2020)
Acta Medica Philippina
; : 1-6, 2020.
Article
en En
| WPRIM
| ID: wpr-979805
Biblioteca responsable:
WPRO
ABSTRACT
Objectives@#The study was done to determine the diagnostic accuracy of rapid antibody tests (RATs) in detecting SARS-CoV-2 infection among asymptomatic employees returning to work. The study also aimed to determine the prevalence of asymptomatic RT-PCR-confirmed COVID-19 infection among these workers. @*Methods@#The study was a retrospective cohort of asymptomatic employees involved in the manufacturing, marketing, and sales of pharmaceutical, consumer, and animal products in the Philippines. They underwent screening for COVID-19 using both rapid antibody and RT-PCR tests as part of the return-to-work company policy from June 1 to July 31, 2020. The sensitivity and specificity of the RATs were computed using RT-PCR as the reference standard. The prevalence of RT-PCR positive COVID-19 infections among asymptomatic returning workers was also determined. @*Results@#Asymptomatic workers (n=5,585) were simultaneously tested for COVID-19 using RAT and RT-PCR. The sensitivity of a positive IgG and IgM was 23.9 (95% CI: 22.8 – 25.0), while the specificity was 93.3 (95% CI: 92.6 - 93.9). The prevalence of RT-PCR identified COVID-19 infection among asymptomatic workers was 4.9% (95% CI: 4.4 – 5.5). @*Conclusion@#The utility of RATs as a screening tool to detect asymptomatic COVID-19 individuals is limited due to its low sensitivity compared to RT-PCR.
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Base de datos:
WPRIM
Asunto principal:
Sensibilidad y Especificidad
/
SARS-CoV-2
/
COVID-19
Idioma:
En
Revista:
Acta Medica Philippina
Año:
2020
Tipo del documento:
Article