Mutation of dentin sialophosphoprotein and hereditary malformations of dentin / 中华口腔医学杂志
Chinese Journal of Stomatology
; (12): 17-24, 2023.
Article
en Zh
| WPRIM
| ID: wpr-970750
Biblioteca responsable:
WPRO
ABSTRACT
The classification as well as the clinical manifestations of hereditary malformations of dentin are of great concern and have been deeply elucidated. The understanding of its genetic basis also increases progressively. Dentin sialophosphoprotein (DSPP) is the pathogenic gene of dentinogenesis imperfecta type Ⅱ, dentinogenesis imperfecta type Ⅲ and dentin dysplasia type Ⅱ. In this article, the classification of DSPP mutations as well as the resultant dysfunction of the mutant DSPP are summarized respectively and the corresponding clinical manifestations are analyzed. This work will provide a reference for the diagnosis and treatment of hereditary malformations of dentin.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Fosfoproteínas
/
Sialoglicoproteínas
/
Proteínas de la Matriz Extracelular
/
Dentina
/
Dentinogénesis Imperfecta
/
Mutación
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Stomatology
Año:
2023
Tipo del documento:
Article