Application of microneedle-assisted percutaneous drug delivery system in treatment of rheumatoid arthritis:a review / 中国中药杂志
Zhongguo Zhong Yao Za Zhi
; (24): 13-21, 2023.
Article
en Zh
| WPRIM
| ID: wpr-970496
Biblioteca responsable:
WPRO
ABSTRACT
Rheumatoid arthritis(RA) is a chronic degenerative joint disease characterized by inflammation. Due to the complex causes, no specific therapy is available. Non-steroidal anti-inflammatory agents and corticosteroids are often used(long-term, oral/injection) to interfere with related pathways for reducing inflammatory response and delaying the progression of RA, which, however, induce many side effects. Microneedle, an emerging transdermal drug delivery system, is painless and less invasive and improves drug permeability. Thus, it is widely used in the treatment of RA and is expected to be a new strategy in clinical treatment. This paper summarized the application of microneedles in the treatment of RA, providing a reference for the development of new microneedles and the expansion of its clinical application.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Artritis Reumatoide
/
Administración Cutánea
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Preparaciones Farmacéuticas
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Antiinflamatorios no Esteroideos
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Sistemas de Liberación de Medicamentos
/
Agujas
Límite:
Humans
Idioma:
Zh
Revista:
Zhongguo Zhong Yao Za Zhi
Año:
2023
Tipo del documento:
Article