Research progress on the molecular regulatory mechanism of exosome biogenesis / 中华危重病急救医学
Chinese Critical Care Medicine
; (12): 429-433, 2022.
Article
en Zh
| WPRIM
| ID: wpr-955985
Biblioteca responsable:
WPRO
ABSTRACT
Exosomes are small vesicles with a diameter of about 40-160 nm actively secreted by cells. They participate in a variety of pathophysiological processes and are closely related to the occurrence and development of diseases. As a newly carrier of intercellular communication and circulating biomarkers of disease diagnosis and prognosis, exosomes have attracted great attention for their potential clinical applications. However, many aspects such as exosome biogenesis, targeted transport, and mechanism of action are still unclear. This paper focuses on the exosome biogenesis, summarizes the exosome biogenesis pathways, and describes relevant molecular modulation mechanisms of importance. And this review provides a theoretical basis for disease treatment based on regulating exosome production.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Critical Care Medicine
Año:
2022
Tipo del documento:
Article