Objective:To evaluate the effect of quick response (QR) code health education in clinical nursing of vascular surgery.Methods:A total of 538 patients hospitalized in the vascular Surgery department of Beijing Friendship Hospital affiliated to Capital Medical University from April 2020 to December 2020 were selected as the research subjects. The subjects were divided into control group ( n = 272) and experimental group ( n = 266) by random number table method. Patients in the control group received health education by conventional oral methods, while patients in the experimental group received health education by means of QR code health education. After health education, the compliance, duration of health education, disease knowledge awareness rate and patient satisfaction rate were compared between the two groups of patients. Results:The compliance rate in medication compliance, outpatient follow-up visit, living habits in the experimental group were higher than those in the control group ( χ2 values were 2.96-4.82, P<0.05). The average length of health education by nurses in the experimental group was (4.53 ± 3.21) min, which was lower than (10.15 ± 1.03) min in the control group. The difference was statistically significant ( t = 3.41, P<0.05). The average score of health knowledge in the experimental group was 91.46 ± 4.77, which was higher than 85.37 ± 3.25 in the control group. The difference was statistically significant ( t = 8.59, P<0.05). The satisfaction rate of patients in the experimental group was 96.62% (257/266), which was higher than 75.37% (205/272) in the control group. The difference was statistically significant ( χ2= 63.04, P<0.05). Conclusions:The application of QR code health education in clinical nursing of vascular surgery can improve patient satisfaction rate, save health education time and increase the awareness rate of patients to disease knowledge. This kind of education is worthy of vigorous promotion in clinical practice.