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Progress on T cell subsets and pathogenesis of asthma / 国际儿科学杂志
Article en Zh | WPRIM | ID: wpr-954068
Biblioteca responsable: WPRO
ABSTRACT
Asthma is a common chronic airway inflammatory disease, which is characterized by airway stenosis, airway wall thickening and increased mucus secretion followed by reversible airflow restriction.At present, asthma is considered to be a complex and heterogeneous disease, and its pathogenesis remains elusive.There are diverse immune cells involved in the formation of asthma, including T lymphocytes, eosinophils, neutrophils, etc.Due to the continuous renewal of classification and function of T lymphocytes subsets, their role in asthma has attracted more attention.Here, this review aims to summarize the immunological characteristics and roles of different T cell subsets in asthma, and highlight the new findings of T cell subsets in the pathogenesis of severe asthma, leading to provide inspiration and help for the study of the immunology pathogenesis, clinical diagnosis, treatment and prognosis in asthma.
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Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: International Journal of Pediatrics Año: 2022 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: International Journal of Pediatrics Año: 2022 Tipo del documento: Article