Research progress on Astragali Radix and prediction of its quality markers (Q-markers) / 中国中药杂志
Zhongguo Zhong Yao Za Zhi
; (24): 1754-1764, 2022.
Article
en Zh
| WPRIM
| ID: wpr-928172
Biblioteca responsable:
WPRO
ABSTRACT
Astragali Radix, a medicinal herb for invigorating Qi, has anti-aging, anti-tumor, immunoregulatory, blood sugar-and lipid-lowering, anti-fibrosis, anti-radiation and other pharmacological effects. This article reviewed the studies about the chemical components and pharmacological effects of Astragali Radix. According to the theory of quality markers(Q-markers) of Chinese medicinal materials, we predicted the Q-markers of Astragali Radix from traditional efficacy, chemical component validity, measurability, plant phylogeny, and pharmacokinetis. The results showed that total polysaccharides, flavonoids(e.g., calycosin-7-O-β-D-glucoside, formononetin, calycosin, quercetin, and ononin), and saponins(e.g., astragalosides Ⅱ, Ⅲ, and Ⅳ) can be taken as the main Q-markers. This review lays a foundation for regulating the quality research and standard establishment of Astragali Radix, and benefits the control and quality supervision of the production process of Astragali Radix and its related products.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Flavonoides
/
Medicamentos Herbarios Chinos
/
Cromatografía Líquida de Alta Presión
/
Raíces de Plantas
/
Planta del Astrágalo
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
Zhongguo Zhong Yao Za Zhi
Año:
2022
Tipo del documento:
Article