Immunomodulatory effects of flazin from Crassostrea sikamea on splenic lymphocytes of Sprague-Dawley rats / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 836-843, 2021.
Article
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| WPRIM
| ID: wpr-922766
Biblioteca responsable:
WPRO
ABSTRACT
Crassostrea sikamea (C.sikamea) is an important edible and medicinal seafood in China. In the present study, a compound named flazin was separated and identified from the ethyl acetate extract of C.sikamea (EAECs) for the first time. In addition, the 3-(4, 5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetra zolium (MTS) assay revealed that EAECs and flazin inhibited the transformation of splenic lymphocytes in vitro. Moreover, flazin (20 μg·mL
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Bazo
/
Carbolinas
/
Linfocitos
/
Ratas Sprague-Dawley
/
Crassostrea
/
Furanos
Límite:
Animals
Idioma:
En
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2021
Tipo del documento:
Article