Retrospective Analysis of Hematological Phenotypes in Patients with Gene Mutation and Deletion α-Thalassemia / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1262-1265, 2021.
Article
en Zh
| WPRIM
| ID: wpr-888549
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To explore the differences between hematological phenotypes of patients with different genotypes in gene mutations and deletion α- thalassemia.@*METHODS@#By screening the α- thalassemia gene test results in the First Affiliated Hospital, Sun Yat-Sen University from January 2015 to April 2020, the patients with mutation and deletion α- thalassemia were obtained, then the differences between hematological phenotypes of patients with different genotypes were analyzed.@*RESULTS@#There were 96 patients with mutation combined with deletion α- thalassemia from the results of 24 054 α- thalassemia patients screened out, including 79 patients with non-deletion Hb H disease (α@*CONCLUSION@#The hematological phenotype changes caused by α
Texto completo:
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Base de datos:
WPRIM
Asunto principal:
Fenotipo
/
Estudios Retrospectivos
/
Talasemia alfa
/
Genotipo
/
Mutación
Tipo de estudio:
Observational_studies
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Experimental Hematology
Año:
2021
Tipo del documento:
Article