Role of antibiotics in tumor development and immunotherapy / 国际肿瘤学杂志
Journal of International Oncology
; (12): 48-51, 2021.
Article
en Zh
| WPRIM
| ID: wpr-882507
Biblioteca responsable:
WPRO
ABSTRACT
In recent years, immunotherapy with immune checkpoint inhibitor (ICI) as the representative drug has become an important treatment method for advanced malignant tumors. Preclinical studies have found that disorders of the gut microbiota can reduce the clinical benefit of patients treated with ICI. The latest data indicate that antibiotics may further affect the occurrence and development of tumors and the efficacy of immunotherapy by changing the abundance and composition of intestinal microbiota. To sum up the role of anti-biotics in the immunotherapy of advanced malignant tumor may provide a new idea for the optimization of treatment strategies for patients with advanced cancer.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Año:
2021
Tipo del documento:
Article