Macrophage-derived small extracellular vesicles promote biomimetic mineralized collagen-mediated endogenous bone regeneration / 国际口腔科学杂志·英文版
International Journal of Oral Science
; (4): 33-33, 2020.
Article
en En
| WPRIM
| ID: wpr-880849
Biblioteca responsable:
WPRO
ABSTRACT
Macrophages play an important role in material-related immune responses and bone formation, but the functionality of macrophage-derived extracellular vesicles (EVs) in material-mediated bone regeneration is still unclear. Here, we evaluated intracellular communication through small extracellular vesicles (sEVs) and its effects on endogenous bone regeneration mediated by biomimetic intrafibrillarly mineralized collagen (IMC). After implantation in the bone defect area, IMC generated more neobone and recruited more mesenchymal stem cells (MSCs) than did extrafibrillarly mineralized collagen (EMC). More CD63
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Osteogénesis
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Regeneración Ósea
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Diferenciación Celular
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Colágeno
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Biomimética
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Vesículas Extracelulares
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Macrófagos
Idioma:
En
Revista:
International Journal of Oral Science
Año:
2020
Tipo del documento:
Article