Altered Functional Connectivity of the Default Mode Network in Low-Empathy Subjects
Yonsei med. j
; Yonsei med. j;: 1061-1065, 2017.
Article
en En
| WPRIM
| ID: wpr-87980
Biblioteca responsable:
WPRO
ABSTRACT
Empathy is the ability to identify with or make a vicariously experience of another person's feelings or thoughts based on memory and/or self-referential mental simulation. The default mode network in particular is related to self-referential empathy. In order to elucidate the possible neural mechanisms underlying empathy, we investigated the functional connectivity of the default mode network in subjects from a general population. Resting state functional magnetic resonance imaging data were acquired from 19 low-empathy subjects and 18 medium-empathy subjects. An independent component analysis was used to identify the default mode network, and differences in functional connectivity strength were compared between the two groups. The low-empathy group showed lower functional connectivity of the medial prefrontal cortex and anterior cingulate cortex (Brodmann areas 9 and 32) within the default mode network, compared to the medium-empathy group. The results of the present study suggest that empathy is related to functional connectivity of the medial prefrontal cortex/anterior cingulate cortex within the default mode network. Functional decreases in connectivity among low-empathy subjects may reflect an impairment of self-referential mental simulation.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Imagen por Resonancia Magnética
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Corteza Prefrontal
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Empatía
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Neuroimagen Funcional
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Giro del Cíngulo
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Memoria
Idioma:
En
Revista:
Yonsei med. j
Año:
2017
Tipo del documento:
Article