Effect of acupuncture on intestinal flora and TLR4 in brain and intestinal tissues in rats with stress gastric ulcer / 中国针灸
Chinese Acupuncture & Moxibustion
; (12): 413-419, 2021.
Article
en Zh
| WPRIM
| ID: wpr-877631
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To observe the effect of acupuncture at "Guanyuan" (CV 4) and "Xiajuxu" (ST 39) on intestinal flora and Toll-like receptors-4 (TLR4) in brain and intestinal tissue in rats with stress gastric ulcer (SGU), and to explore the possible mechanism of acupuncture for SGU.@*METHODS@#Thirty-one male SD rats were randomly divided into a blank group (@*RESULTS@#Compared with the blank group, the gastric mucosal damage index was significantly increased in the model group (@*CONCLUSION@#Acupuncture at "Guanyuan" (CV 4) and "Xiajuxu" (ST 39) could alleviate SGU in rats, and its mechanism may be related to increasing the diversity of intestinal flora, promoting the disorder of intestinal flora to normal, and reducing the overexpression of TLR4 in brain and intestinal tissues.
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Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Úlcera Gástrica
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Encéfalo
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Puntos de Acupuntura
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Terapia por Acupuntura
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Ratas Sprague-Dawley
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Receptor Toll-Like 4
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Microbioma Gastrointestinal
Límite:
Animals
Idioma:
Zh
Revista:
Chinese Acupuncture & Moxibustion
Año:
2021
Tipo del documento:
Article