NLRP3 inflammasomes and skin diseases / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12): 236-238, 2020.
Article
en Zh
| WPRIM
| ID: wpr-870259
Biblioteca responsable:
WPRO
ABSTRACT
NOD-like receptor protein 3 (NLRP3) inflammasomes play an important role in innate immunity.It can induce the maturation and release of cytokines interleukin (IL)-1β and IL-18 by activating caspase-1,and participate in a variety of host immunoinflammatory responses.Once the regulation of NLRP3 inflammasomes is unbalanced,excessive IL-1β and IL-18 may be produced,triggering a series of inflammatory diseases.NLRP3 inflammasome activation plays important roles in skin diseases such as acne,psoriasis,pyoderma gangrenosum,polymyositis/dermatomyositis and bullous pemphigoid.This review summarizes research progress in NLRP3 inflammasomes in skin diseases.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Dermatology
Año:
2020
Tipo del documento:
Article