Effects from Side Branch Diameter of Intracranial Aneurysm on Hemodynamic Parameters after Flow Diverter Implantation / 医用生物力学
Journal of Medical Biomechanics
; (6): E403-E409, 2020.
Article
en Zh
| WPRIM
| ID: wpr-862361
Biblioteca responsable:
WPRO
ABSTRACT
Objective To comprehensively consider the effect of low diverter (FD) implantation on aneurysmal sac and its branches, so as to provide references for making a more reasonable surgical strategy for intracranial aneurysm embolization in clinical practice. Methods Based on computational fluid dynamics (CFD) method, the FD implantation procedure was simulated by using porous media model innovatively. Changes in hemodynamic parameters of aneurysmal sac and side branch with different diameters before and after FD implantation were compared and analyzed, such as blood flow field, velocity, wall pressure and wall shear stress (WSS). Results FD changed the hemodynamic characteristics of aneurysms. The blood flow velocity decreased significantly. The WSS on aneurysmal neck increased, while the difference of WSS between proximal and distal cervical area reduced conversely. Different side branch diameters of vessels had different effects on hemodynamic characteristic changes. The larger diameter would cause the greater blood flow reduction in side branch after FD implantation, but the decrease in velocity of aneurysmal sac and pressure on aneurysmal roof became smaller simultaneously. Meanwhile, the increase of WSS on aneurysmal neck was inversely proportional to the diameter of side branch. Conclusions The larger branch diameter of vessels would cause the worse effect of FD embolization therapy for intracranial aneurysm, worse atherosclerosis improvements and greater possibilities of branch occlusion or other ischemic complications. Doctors should pay more attention to such cases in FD interventional intravascular embolization in clinic.
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
Journal of Medical Biomechanics
Año:
2020
Tipo del documento:
Article