Quality Control Method of Xinmaishu Capsules / 中国药学杂志
Chinese Pharmaceutical Journal
; (24): 1843-1846, 2018.
Article
en Zh
| WPRIM
| ID: wpr-858166
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE: To establish an HPLC method for determination of ferulic acid in Ligusticum Wallichii,which is the active ingredient of Xinmaishu capsules. METHODS: The content was determined by HPLC. The analysis was carried out on C18(4.6 mm×250 mm,5 μm) column. The mobile phase consisted of acetonitrile-0.3% acetic acid(13∶87). The flow rate was 1.0 mL·min-1, and the UV detection wavelength was set at 322 nm. RESULTS: The linearity range of the calibration curve for ferulic acid was from 1.0 to 10.0 μg·mL-1 (r=0.999 8). The average recovery rate was 99.57% with RSD of 0.75%(n=9). CONCLUSION: This method is sensitive, accurate,reproducible and simple. It can be used for the quality control of ferulic acid in Xinmaishu capsules.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmaceutical Journal
Año:
2018
Tipo del documento:
Article