A new antiviral isoquinoline alkaloid from Thalictrum glandulosissimum / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2568-2570, 2020.
Article
en Zh
| WPRIM
| ID: wpr-828044
Biblioteca responsable:
WPRO
ABSTRACT
A new isoquinoline alkaloid(1) has been isolated from the whole plant of Thalictrum glandulosissimum by using various chromatographic techniques, including silica gel, sephadex, MCI-gel resin, and RP-HPLC, and its structure was determined as 1-(6-hydroxy-7-methylisoquinolin-1-yl) ethantone by physicochemical properties and spectroscopic data. This compound was evaluated for anti-tobacco mosaic virus(TMV) activity. The results showed that it had prominent anti-TMV activity with inhibition rates of 28.4%. This rate was closed to that of positive control.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Antivirales
/
Virus del Mosaico del Tabaco
/
Thalictrum
/
Alcaloides
/
Isoquinolinas
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2020
Tipo del documento:
Article