Clinical characteristics of histoplamosis in 8 patients: case report and literature review / 中南大学学报(医学版)
Zhongnan Daxue xuebao. Yixue ban
; (12): 644-652, 2016.
Article
en Zh
| WPRIM
| ID: wpr-814985
Biblioteca responsable:
WPRO
ABSTRACT
To explore the clinical characteristics, imaging manifestation, diagnosis and treatment for histoplasmosis and to improve therapeutic level, we retrospectively analyzed the clinical data of 8 patients with biopsy-confirmed histoplasmosis from 2004 to 2014 in the Second Xiangya Hospital of Central South University and reviewed relevant literatures. The main clinical symptoms of histoplasmosis included fever, cough, expectoration, chest pain, blood-stained sputum, lymphadenectasis, etc. The major lung imaging features were mass, node or pneumonia-like performance. No case was diagnosed as histoplasimosis firstly. Four patients whose imaging manifestations were focal pulmonary lesion received lobectomy of lung lesions or wedge resection. Clinical and imaging manifestations in 3 patients, who treated with amphotericin B or its liposomal, itraconazole or fluconazole, were improved. The clinical symptoms and imaging findings of histoplasmosis are nonspecific. It is easy for the physicians to misdiagnose histoplasmosis as bacterial infection, lung cancer, tuberculosis lymphoma, etc. Therefore, it is significant and necessary to carry out multiple biopsies combined with multiple etiological examinations for patients with difficult diagnosis.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Neumonía
/
Esputo
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Biopsia
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Anfotericina B
/
Estudios Retrospectivos
/
Errores Diagnósticos
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Histoplasmosis
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Pulmón
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Neoplasias Pulmonares
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Humans
Idioma:
Zh
Revista:
Zhongnan Daxue xuebao. Yixue ban
Año:
2016
Tipo del documento:
Article