MicroRNAs and nonresolving inflammation-related cancer / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 639-644, 2013.
Article
en Zh
| WPRIM
| ID: wpr-814829
Biblioteca responsable:
WPRO
ABSTRACT
The link between nonresolving inflammation and cancer is well documented. On the one hand, epidemiologic evidence supports that approximately 25% of all human cancer worldwide is caused by nonresolving inflammation. On the other hand, inflammatory cells are found in the microenvironment of most, if not all, tumors. In the tumor micro-environment, inflammatory cells and molecules influence almost every aspect of cancer. MicroRNAs (miRNAs) participate in the initiation and progression of nonresolving inflammation-related cancer by regulating the key genes and related signaling pathways. Further investigation into the molecular mechanisms by which miRNAs carry out their functions will be of great value in the prevention, early diagnosis, and treatment of tumors.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Enfermedad Crónica
/
Mediadores de Inflamación
/
MicroARNs
/
Alergia e Inmunología
/
Microambiente Tumoral
/
Genética
/
Inflamación
/
Neoplasias
Tipo de estudio:
Screening_studies
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Central South University(Medical Sciences)
Año:
2013
Tipo del documento:
Article