Application and curative effect of plasma exchange in myasthenia gravis patients with thymectomy / 中南大学学报(医学版)
Zhongnan Daxue xuebao. Yixue ban
; (12): 1089-1092, 2007.
Article
en Zh
| WPRIM
| ID: wpr-813944
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To explore the application of plasma exchange in myasthenia gravis (MG) patients with thymectomy, and to evaluate its curative effects.@*METHODS@#The clinical data of 50 patients with thymectomy were analyzed retrospectively, and the patients were divided into Group A (23 cases, undergoing thymectomy and plasma exchange) and Group B (27 cases, undergoing thymectomy). The difference of serum concentration of AChRab was examined by ELISA, and the time of auxiliary breath, crisis of myasthenia and clinical evaluation in the 2 groups were compared.@*RESULTS@#Serum concentration of AChRab in Group A descended obviously after the plasma exchange. One day and one week after the operation, the AChRab concentration in Group A was obviously lower than that in Group B, but there was no difference one month after the operation. One week after the operation, the time of auxiliary breath,crisis of myasthenia and clinical evaluation in Group A were less than those in Group B.@*CONCLUSION@#Plasma exchange together with thymectomy can improve the temporary curative effects in patients with MG. It is safe and effective for MG.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Intercambio Plasmático
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Cirugía General
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Timectomía
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Estudios Retrospectivos
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Resultado del Tratamiento
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Métodos
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Miastenia Gravis
Tipo de estudio:
Observational_studies
Límite:
Adolescent
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Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Zhongnan Daxue xuebao. Yixue ban
Año:
2007
Tipo del documento:
Article