Association between red blood cell volume distribution width and osteophytes: A cross-sectional study / 中南大学学报(医学版)
Zhongnan Daxue xuebao. Yixue ban
; (12): 892-897, 2018.
Article
en Zh
| WPRIM
| ID: wpr-813178
Biblioteca responsable:
WPRO
ABSTRACT
To investigate the association between red blood cell volume distribution width (RDW) and osteophytes.
Methods: This cross-sectional study was conducted in the Department of Health Examination Center of Xiangya Hospital, Central South University in Changsha, Hunan Province, China. A total of 8 334 subjects were included in this study. The severity of osteophytes was graded using the criteria of the Osteoarthritis Research Society International (OARSI). Osteophytes incident was defined as at least one side of the knee had a osteophytes grade ≥1. According to the quartiles of the RDW level, the subjects were divided into 4 groups. Multivariate logistic regression analysis was used to calculate the odds ratio (OR) and the 95% confidence interval (CI) of the knee osteophytes incidence between each RDW group and the lowest level group. Tests for linear trends were conducted based on logistic regression using a median variable of RDW level in each category.
Results: Quartile 1 (Q1), RDW≤9.78; Q2, 9.7813.10. The multivariable adjusted ORs (95%CI) of the prevalence of osteophytes were 1.38 (1.06 to 1.79) in the second percentile interval, and 1.27 (0.97 to 1.66) and 1.50 (1.15 to 1.94) in the third and fourth percentile interval, respectively. Test for linear trends suggested that there was a positive association between the RDW level and the risk of knee osteophytes incidence (P=0.019).
Conclusion: The risk of osteophytes incidence increases with the increasing RDW levels.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Sangre
/
Índice de Severidad de la Enfermedad
/
Intervalos de Confianza
/
Oportunidad Relativa
/
China
/
Epidemiología
/
Incidencia
/
Estudios Transversales
/
Factores de Riesgo
/
Volumen de Eritrocitos
Tipo de estudio:
Etiology_studies
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Incidence_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
Zhongnan Daxue xuebao. Yixue ban
Año:
2018
Tipo del documento:
Article