Clinical Outcomes of Increased Nuchal Translucency in Three Years / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
; : 2151-2155, 2003.
Article
en Ko
| WPRIM
| ID: wpr-79244
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE: To evaluate the relationship between increased nuchal translucency (NT) and abnormal pregnancy outcomes. METHODS: From January 1999 to December 2001, The 298 fetuses of increased nuchal translucency (>or=2.5 mm) in period of 10-14 weeks gestation were reviewed retrospectively. Amniocentesis and high resolution ultrasonography during second trimester were done for all cases. We analyzed septation within NT, karyotypes, structural anomalies, and adverse pregnancy outcomes such as spontaneous abortion, intrauterine fetal death and preterm delivery. RESULTS: The mean age of the patients was 30.5 +/- 3.5 years. The mean gestational age and CRL were 12.5 +/- 0.95 weeks and 6.5 +/- 1.15 mm. We observed 18 (6%) cases of abnormal karyotypes. 7/46 (15.2%) fetuses with internal septation had abnormal karyotype and 11/252 (4.4%) fetuses without internal septation had abnormal karyotype (p=0.013). Among the 280 fetuses with normal karyotype, 8 (2.8%) fetuses had structural anomalies and 18 (6.4%) fetuses had adverse pregnancy outcomes. The chromosomal abnormality and structural anomaly were significantly increased in the group of nuchal translucency thickness above 3.5 mm (p=0.001). CONCLUSION: Increased nuchal translucency is related with chromosomal abnormality and abnormal pregnancy outcomes.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Segundo Trimestre del Embarazo
/
Resultado del Embarazo
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Aborto Espontáneo
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Estudios Retrospectivos
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Aberraciones Cromosómicas
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Ultrasonografía
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Edad Gestacional
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Medida de Translucencia Nucal
/
Muerte Fetal
/
Feto
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
Ko
Revista:
Korean Journal of Obstetrics and Gynecology
Año:
2003
Tipo del documento:
Article