The Characteristics of Incidental Pituitary Microadenomas in 120 Korean Forensic Autopsy Cases
Journal of Korean Medical Science
; : S61-S65, 2007.
Article
en En
| WPRIM
| ID: wpr-79230
Biblioteca responsable:
WPRO
ABSTRACT
To investigate the characteristics of incidental pituitary microadenomas, we examined 120 pituitary glands from Korean forensic autopsy cases, from which eight tumors were identified (incidence 6.7%). The average age of the affected subjects was 50 yr (range: 33-96 yr) with a female predominance. The maximum diameters of the tumors ranged from 0.4 to 5.4 mm (mean: 2.8 mm). Immunohistochemical analysis of pituitary hormones revealed three growth hormone-secreting adenomas, one prolactin-producing adenoma, one gonadotropin-producing adenoma, one plurihormonal adenoma, and two null cell adenomas. MIB-1 staining for Ki-67 antigen showed no positive expression. The microvessel density (MVD) of the pituitary microadenomas ranged from 2.3 to 11.6% (mean: 5.3%) and was significantly lower than that of nonneoplastic pituitary glands (11.9-20.1%, mean: 14.8%). Our study provides reference data on incidental pituitary microadenomas in the Korean population.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Hormonas Hipofisarias
/
Neoplasias Hipofisarias
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Autopsia
/
Inmunohistoquímica
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Adenoma
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Antígeno Ki-67
/
Corea (Geográfico)
/
Microcirculación
Tipo de estudio:
Prognostic_studies
Límite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
Journal of Korean Medical Science
Año:
2007
Tipo del documento:
Article