Nosocomial Pseudomonas putida Bacteremia: High Rates of Carbapenem Resistance and Mortality / 전남의대학술지
Chonnam Medical Journal
; : 91-95, 2012.
Article
en En
| WPRIM
| ID: wpr-788240
Biblioteca responsable:
WPRO
ABSTRACT
Previously, Pseudomonas putida was considered a low-virulence pathogen and was recognized as a rare cause of bacteremia. Recently, however, multidrug-resistant and carbapenem-resistant P. putida isolates have emerged, causing difficult-to-treat nosocomial infections in seriously ill patients. Currently, the outcome of multidrug-resistant or carbapenem-resistant P. putida bacteremia remains uncertain. Here, we report 18 cases of P. putida bacteremia with high rates of carbapenem resistance and mortality. From January 2005 through December 2011, all cases of nosocomial P. putida bacteremia were identified and analyzed at Chonnam National University Hospital and Chonnam National University Hwasun Hospital. Electronic medical records were reviewed retrospectively. Four (22%) and five (23%) of 18 P. putida isolates were resistant to imipenem and meropenem, respectively. Common primary infection sites were central venous catheter (7, 39%), pneumonia (5, 28%), and cholangitis (2, 11%). Fourteen (78%) patients had indwelling devices related to the primary site of infection. The 30-day mortality rate was 39% (7/18): 40% (2/5) in patients with carbapenem-resistant P. putida bacteremia vs. 38% (5/13) in patients with carbapenem-susceptible P. putida bacteremia. Nosocomial P. putida bacteremia showed high resistance rates to most potent beta-lactams and carbapenems and was associated with high mortality rates.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Neumonía
/
Pseudomonas
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Resistencia a Medicamentos
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Carbapenémicos
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Tienamicinas
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Colangitis
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Imipenem
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Infección Hospitalaria
/
Estudios Retrospectivos
/
Pseudomonas putida
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Chonnam Medical Journal
Año:
2012
Tipo del documento:
Article