Serum CRP level is positively correlated with the cardiovascular disease in dialysis patients / 대한내과학회지
Korean Journal of Medicine
; : 668-674, 2002.
Article
en Ko
| WPRIM
| ID: wpr-77933
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND: Atherosclerosis, a major problem in patients undergoing chronic dialysis treatment, has been characterized as an inflammatory disease. Cardiovascular disease is the major cause of mortality, accouting for approximately half of all deaths in this population. The present study was aimed whether CRP, an important inflammatory marker, might be associated with cardiovascular risk in dialysis patients. METHODS: We performed retrospective study in 77 dialysis patients. Patients were divided into the elevated CRP group (>8 mg/L, n=11) and the normal CRP group (8 mg/L) showed significant higher cardiovascular events (by chi-squre test, p=0.032). BMI, smoking, alcohol, dialysis modality, lipid parameters, BUN, serum creatinine, serum protein, serum albumin and seurm TIBC did not show significant difference between two groups. Correlation between CRP and other biochemical parameters was analysed. Only ESR was positively correlated with CRP. In a subsequent analysis, elevated CRP group had significantly higher cardiovascular risk (by stepwise logistic regression method, odd ratio = 6.59;95% CI, 1.13 to 38.28). CONCLUSION: These results suggest that CRP level is correlated with cardiovascular risk in dialysis patients.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Humo
/
Proteína C-Reactiva
/
Albúmina Sérica
/
Enfermedades Cardiovasculares
/
Fumar
/
Índice de Masa Corporal
/
Modelos Logísticos
/
Estudios Retrospectivos
/
Mortalidad
/
Diálisis Renal
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
/
Male
Idioma:
Ko
Revista:
Korean Journal of Medicine
Año:
2002
Tipo del documento:
Article