Recent advances in cell sheet technology for bone and cartilage regeneration: from preparation to application / 国际口腔科学杂志·英文版
International Journal of Oral Science
; (4): 17-17, 2019.
Article
en En
| WPRIM
| ID: wpr-772267
Biblioteca responsable:
WPRO
ABSTRACT
Bone defects caused by trauma, tumour resection, infection and congenital deformities, together with articular cartilage defects and cartilage-subchondral bone complex defects caused by trauma and degenerative diseases, remain great challenges for clinicians. Novel strategies utilising cell sheet technology to enhance bone and cartilage regeneration are being developed. The cell sheet technology has shown great clinical potential in regenerative medicine due to its effective preservation of cell-cell connections and extracellular matrix and its scaffold-free nature. This review will first introduce several widely used cell sheet preparation systems, including traditional approaches and recent improvements, as well as their advantages and shortcomings. Recent advances in utilising cell sheet technology to regenerate bone or cartilage defects and bone-cartilage complex defects will be reviewed. The key challenges and future research directions for the application of cell sheet technology in bone and cartilage regeneration will also be discussed.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Regeneración
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Huesos
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Regeneración Ósea
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Cartílago Articular
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Ingeniería de Tejidos
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Andamios del Tejido
Idioma:
En
Revista:
International Journal of Oral Science
Año:
2019
Tipo del documento:
Article