Correlation analysis of antibody titer and immune balance after infection of mycoplasma pneumoniae in children with bronchial asthma / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
; (12): 2386-2388, 2019.
Article
en Zh
| WPRIM
| ID: wpr-753801
Biblioteca responsable:
WPRO
ABSTRACT
To study the correlation of antibody titer and immune balance after infection of myco-plasma pneumoniae in children with bronchial asthma.Methods From October 2010 to August 2015,108 children with bronchial asthma infected with mycoplasma pneumoniae were selected.There were 71 patients in the observation group,children with mycoplasma pneumoniae antibody titers ＞1:160,and 37 cases were selected as control group , mycoplasma pneumonia antibody titer ≤1 : 160.The titer of mycoplasma antibody , serum interferon gamma (IFN-γ),interleukin-4(IL-4) and interleukin -17( IL-17) were measured.Results The serum IFN -γ, IL-4 and IL-17 levels in the control group were (41.04 ±3.13) μg／L,(17.04 ±3.16) μg／L and (30.81 ± 4.23)μg／L,respectively,which in the observation group were (33.26 ±3.17) μg／L,(24.15 ±5.09) μg／L and (41.29 ±5.09) μg／L,respectively.The serum IL-4 and IL-17 levels of the observation group were significantly higher than those of the control group (t＝5.126,3.429,all P＜0.05).After infection of mycoplasma pneumoniae ,the serum IFN-γin the observation group decreased significantly ( t ＝4.168,P＜0.05).Conclusion The titer of antibody after mycoplasma pneumoniae infection in children with bronchial asthma is closely related to the immune balance.The higher the antibody titer ,the more serious the immune imbalance.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Año:
2019
Tipo del documento:
Article