The clinical effects of hospitalization in a low pollutant room on atopic dermatitis
Asia Pacific Allergy
; (4): 87-92, 2011.
Article
en En
| WPRIM
| ID: wpr-749865
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND: Environmental pollutants are thought to be one of major triggers of atopic dermatitis (AD). OBJECTIVE: We attempted to evaluate the clinical effects of environment with low indoor pollutant levels on AD management. METHODS: Fifty-one children (mean age 1.7 years) with moderate to severe AD who failed to show improvement with conventional management were recruited. Disease severity was assessed by SCORAD (Scoring of AD) indices. They were admitted in a low pollutant oom for 3-4 days (mean 3.3 days) which was designed to keep low levels of dust, house dust mites, micro-organisms, and indoor air pollutants such as total volatile organic compounds (TVOCs), particulate matter (PM), and so on. Air pollutant levels in the low pollutant room were lower than primary standards defined by the Korean Ministry of Environment. we compared disease severity on admission and after discharge, and the pollutant levels of each patient's home and low pollutant room. RESULTS: The SCORAD was significantly reduced from 42.0 ± 11 .5 to 29.8 ± 8.9 (p < 0.001) by management in a low pollutant room. PM₂.₅, PM₁₀, formaldehyde, TVOCs, carbon dioxide, bacterial suspensions, and indoor molds were significantly higher in the patient's home than low pollutant room. Out of 29 patients who deteriorated after discharge to their home, 8 patients were admitted again, and their SCORAD was rapidly decreased from 53.1 ± 16.2 to 39.2 ± 9.8 (p = 0.036). CONCLUSION: Indoor air pollutants are likely to affect AD in susceptible individuals. Environmental control to lower indoor air pollutant levels might be necessary for better management of AD in some patients.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Suspensiones
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Dióxido de Carbono
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Dermatitis Atópica
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Contaminantes Atmosféricos
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Contaminación del Aire
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Polvo
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Contaminantes Ambientales
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Material Particulado
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Compuestos Orgánicos Volátiles
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Formaldehído
Tipo de estudio:
Guideline
Límite:
Child
/
Humans
Idioma:
En
Revista:
Asia Pacific Allergy
Año:
2011
Tipo del documento:
Article