Seasonal patterns and etiologies of croup in children during the period 2010–2015: A multicenter retrospective study
Allergy, Asthma & Respiratory Disease
; : 78-85, 2019.
Article
en Ko
| WPRIM
| ID: wpr-739515
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: Croup is known to have epidemics in seasonal and biennial trends, and to be strongly associated with epidemics of parainfluenza virus. However, seasonal and annual epidemics of croup have not been clearly reported in Korea. This study aimed to examine the seasonal/annual patterns and etiologies of childhood croup in Korea during a consecutive 6-year period. METHODS: Pediatric croup data were collected from 23 centers in Korea from 1 January 2010 to 31 December 2015. Electronic medical records, including multiplex reverse transcription polymerase chain reaction (RT-PCR) results, demographics and clinical information were cross-sectionally reviewed and analyzed. RESULTS: Overall, 2,598 childhood croup patients requiring hospitalization were identified during the study period. Among them, a total of 927 who underwent RT-PCR were included in the analysis. Males (61.5%) predominated, and most (63.0%) of them were younger than 2 years of age (median, 19 months; interquartile range, 11–31 months). Peak hospitalization occurred in 2010 and 2012 in even-numbered years, and parainfluenza virus (PIV, 39.7%) was the most common cause of childhood croup requiring hospitalization, followed by respiratory syncytial virus (14.9%), human rhinovirus (12.5%), Mycoplasma pneumonaie (10.6%), and human coronavirus (7.3%). CONCLUSION: It is concluded that croup hospitalization has a biennial pattern in even-numbered years. PIV may be the most common cause of childhood croup; however, croup epidemics could be attributed to other viruses.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Virus Sincitiales Respiratorios
/
Rhinovirus
/
Estaciones del Año
/
Crup
/
Demografía
/
Reacción en Cadena de la Polimerasa
/
Estudios Retrospectivos
/
Infecciones por Paramyxoviridae
/
Coronavirus
/
Transcripción Reversa
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspecto:
Determinantes_sociais_saude
Límite:
Child
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
Ko
Revista:
Allergy, Asthma & Respiratory Disease
Año:
2019
Tipo del documento:
Article