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Successful desensitization to fluconazole induced delayed hypersensitivity: A case report
Article en Ko | WPRIM | ID: wpr-739501
Biblioteca responsable: WPRO
ABSTRACT
Fluconazole is a triazole-based first-generation antifungal agent and has excellent effects on candidiasis and cryptococcosis. Hypersensitivity has been reported as a side effect of fluconazole. A 76-year-old female patient used fluconazole for consolidation therapy for cryptococcal meningitis, but showed delayed hypersensitivity with skin rashes and itching sensation of the whole body. For desensitization, was attempted by administering 12-step, 1:1 fluconazole solutions were administered intravenously at sequentially increasing infusion rates. After successful quick desensitization to fluconazole, fluconazole was continuously used as a consolidation therapy for cryptococcal meningitis. We herein report a case of delayed hypersensitivity reaction to fluconazole in consolidation therpy with cryptococcal meningitis who successfully completed desensitization.
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Texto completo: 1 Base de datos: WPRIM Asunto principal: Prurito / Sensación / Candidiasis / Fluconazol / Meningitis Criptocócica / Criptococosis / Exantema / Hipersensibilidad / Hipersensibilidad Tardía Límite: Aged / Female / Humans Idioma: Ko Revista: Allergy, Asthma & Respiratory Disease Año: 2018 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Asunto principal: Prurito / Sensación / Candidiasis / Fluconazol / Meningitis Criptocócica / Criptococosis / Exantema / Hipersensibilidad / Hipersensibilidad Tardía Límite: Aged / Female / Humans Idioma: Ko Revista: Allergy, Asthma & Respiratory Disease Año: 2018 Tipo del documento: Article