PI3Ks in diabetic cardiomyopathy / 中国医师杂志
Journal of Chinese Physician
; (12): 1916-1918, 2018.
Article
en Zh
| WPRIM
| ID: wpr-734051
Biblioteca responsable:
WPRO
ABSTRACT
Diabetic cardiomyopathy refers to the heart disease without coronary artery disease and hypertension,diabetic patients with ventricular dysfunction.The molecular mechanism of diabetic cardiomyopathy remains unclear.Protein and lipid kinase phosphoinositol 3-kinase (PI3Ks) are thought to regulate cardiac damage in diabetes mellitus.This article reviews the role of PI3K subtypes and downstream signal transduction in the pathogenesis of diabetic cardiomyopathy,including cardiac metabolic regulation,contractility,hypertrophy,cardiomyocyte death and inflammation.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of Chinese Physician
Año:
2018
Tipo del documento:
Article