Progress of long non-coding RNA in non-small cell lung cancer / 中国医师进修杂志
Chinese Journal of Postgraduates of Medicine
; (36): 283-288, 2018.
Article
en Zh
| WPRIM
| ID: wpr-700208
Biblioteca responsable:
WPRO
ABSTRACT
Lung cancer is the leading cause of cancer-related deaths worldwide, among which more than half of non-small cell lung cancer had been locally advanced or distant metastasis at the time of diagnosis.Therefore,it has a poor prognosis.In recent years,long non-coding RNA(lncRNA)has drawn great attention in the field of oncology.Abnormally expression of lncRNA plays an important role in the development of non-small cell lung cancer through different transcriptional, post-transcriptional or epigenetic mechanisms.This review summarizes the current literature on lncRNA in non-small cell lung cancer, introduces the functions and influences of lncRNA in the biology of non-small cell lung cancer and highlights its clinical potential value as a tumor biomarker and potential therapeutic target.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Postgraduates of Medicine
Año:
2018
Tipo del documento:
Article