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The variance of HSP70 in cardiac cells of SMDS victims / 中国法医学杂志
Chinese Journal of Forensic Medicine ; (6): 394-396,后插1, 2009.
Article en Zh | WPRIM | ID: wpr-686464
Biblioteca responsable: WPRO
ABSTRACT
Objective This article aims to explore the role of HSP70 in the developing mechanism of SMDS(sudden manhood death syndrome,SMDS)and to investigate the value of it in the early diagnosis of SMDS.Methods By way of immunohistochemieal staining of left,right ventricular musles,sino atrial node and atrioventricular node from 30 cases of SMDS group and 20 cases of control group,we observed and measured the expression of HSP70 and its variance of intensity with graphical analysis software.Results Compared with the control group cases,in cardiac conduction system tissue of SMDS victims.we saw an obviously higher expression and intensity of HSP70(P<0.05).Conclusion As a kind of mediator in stress reaction,HSP70 is involved in the process of protecting the heart from impairment in SMDS,and it can be considerated as a reference index to identify the SMDS.
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Texto completo: 1 Base de datos: WPRIM Tipo de estudio: Screening_studies Idioma: Zh Revista: Chinese Journal of Forensic Medicine Año: 2009 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Tipo de estudio: Screening_studies Idioma: Zh Revista: Chinese Journal of Forensic Medicine Año: 2009 Tipo del documento: Article