A Retrospective Study for the Limited-stage Small Cell Lung Cancer Patients with Combined Modality Treatment:An Analysis of 234 Patients / 医学研究杂志
Journal of Medical Research
; (12)2006.
Article
en Zh
| WPRIM
| ID: wpr-680558
Biblioteca responsable:
WPRO
ABSTRACT
Objective To evaluate the treatment effects of chemotherapy comparing with chemotherapy and radiotherapy in the limited-stage small cell lung cancer (SCLC). Methods 234 patients were cyto-pathologically diagnosed and staged as limited small cell lung cancer. The patients were treated with combined chemotherapy and radiotherapy,in which 22 cases were treated by alone chemotherapy (C),39 patients by chemotherapy plus radiotherapy(C+R),and 173 cases by combined chemotherapy and radiotherapy + chemotherapy (C+R+C). The chemotherapy regimen included CE (or PE),CAP or CAV for 4~6 cycles. Irradiation treatment covering the primary tumor,the ipsilateral hilar nodes and mediastinum was delivered once daily with 6 megavoltage X-ray beam to a median irradiation does of 56 Gy being given in 5~6 weeks. Results The 1-,2-,3-,and 5-year overall survival rates were 76.5%,38.2%,25.3%,15.6% respectively,and the median survival time (MST) was 19 months. There was a significantly difference on the survival rate between C+R+C group and C+R group or C group (P
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Base de datos:
WPRIM
Tipo de estudio:
Observational_studies
Idioma:
Zh
Revista:
Journal of Medical Research
Año:
2006
Tipo del documento:
Article