Tissue distribution of strychnos nux-vomica alkaloids in rats / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1986.
Article
en Zh
| WPRIM
| ID: wpr-678889
Biblioteca responsable:
WPRO
ABSTRACT
AIM To study the tissue distribution of strychnos nux vomica alkaloids in rats. METHODS Rats were given strychnos nux vomica alkaloids intravenously and strychnine(S), brucine(B), strychnine N oxide(SNO), brucine N oxide(BNO) in every tissue was determined by HPLC timely. RESULTS The concentration of S, B, SNO and BNO were high in brain and spinal marrow. CONCLUSION S, B, SNO and BNO all have the ability to permeate blood brain barrier.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Año:
1986
Tipo del documento:
Article