A study of the specific cytotoxic T cell of BALB/c mice detected by LDH / 第三军医大学学报
Journal of Third Military Medical University
; (24)1983.
Article
en Zh
| WPRIM
| ID: wpr-678119
Biblioteca responsable:
WPRO
ABSTRACT
Objective To establish a simple animal model and the cytotoxic T cell(CTL) detecting system for the studies of the effects of CTL on HCV infection. Methods The CTL activity in BLAB/c mice immunized by polypeptides in the core region of HCV was detected with lactic dehydrogenase (LDH) by using SP2/O cells as the target cells. Results CTL activity in BLAB/c mice immunized by polypeptides in the core region of HCV could be detected with LDH. The activity could be enhanced by CPA10(5～23 aa) but inhibited by CPA9(39～74 aa). Conclusion CTL activity in BLAB/c mice can be detected stably by LDH.
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1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of Third Military Medical University
Año:
1983
Tipo del documento:
Article