Association of E23K polymorphism of inwardly rectifying K~+channel 6.2 gene with the phenotype of type 2 diabetes and glucose-lowering effect of gliclazide

Li-Li CHEN; Qiang LI; Hou-Xun XING; Xiao-Wei REN; Yu-Qian SUN; Feng-Chen LIU; Mei-Hua LIANG; Zhong ZHANG; Jin-chao ZHANG

Association of E23K polymorphism of inwardly rectifying K~+channel 6.2 gene with the phenotype of type 2 diabetes and glucose-lowering effect of gliclazide / 中华内分泌代谢杂志

Li-Li CHEN; Qiang LI; Hou-Xun XING; Xiao-Wei REN; Yu-Qian SUN; Feng-Chen LIU; Mei-Hua LIANG; Zhong ZHANG; Jin-chao ZHANG.

Chinese Journal of Endocrinology and Metabolism ; (12)1985.

Article en Zh | WPRIM | ID: wpr-676343

Biblioteca responsable: WPRO

ABSTRACT

ABSTRACT

The influences of E23K polymorphism of inwardly rectifying K~+channel 6.2 (Kir6.2) gene on the clinical phenotype of type 2 diabetes and glucose-lowering effect of gliclazide were investigated.The result showed that E23K polymorphism did not influence glucose-lowering effect of gliclazide,but serum creatinine level of patients with K/K genotype was higher than those of E/E and E/K genotypes (P

Palabras clave

Potassium channel,inwardly rectifying; Polymorphism,single nucleotide; Diabetes mellitus,type 2; Gliclazide

Texto completo

Añadir a Mi BVS

Imprimir

XML

Buscar en Google

Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of Endocrinology and Metabolism Año: 1985 Tipo del documento: Article

Texto completo

Añadir a Mi BVS

Imprimir

XML

Buscar en Google

Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of Endocrinology and Metabolism Año: 1985 Tipo del documento: Article