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Research advances in the effects of thrombospondin-1 on the progress of diabetic retinopathy / 眼科新进展
Article en Zh | WPRIM | ID: wpr-660236
Biblioteca responsable: WPRO
ABSTRACT
Thrombospondin-1,an important extracellular matrix glycoprotein,is recognized as an effective endogenous angiogenesis inhibitor and can affect and regulate the adhesion,motility and proliferation of endothelial cells,as well as closely correlated with the development and progress of tumor and neovascular diseases.In recent years,it has been found that Tsp-1 is associated with many pathologic changes in diabetic retinopathy and is critical for the maintenance of retinal vascular balance.And the mechanism of action of TSP-1 and its role in the development of DR will be reviewed in this paper.
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Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Recent Advances in Ophthalmology Año: 2017 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Recent Advances in Ophthalmology Año: 2017 Tipo del documento: Article