Clinical analysis of cyclophosphamide shock treatment in children with refractory nephropathy / 实用医学杂志
The Journal of Practical Medicine
; (24): 2907-2910, 2017.
Article
en Zh
| WPRIM
| ID: wpr-658359
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the effect and adverse reactions of intravenous cyclophosphamide (CTX) pulse therapy on refractory nephrotic syndrome (RNS) in children. Methods Retrospective study was carried on 102 patients with RNS treated with high dose CTX impact treatment in The First Hospital Affiliated to Guangxi Medical University from August 2006 to August 2016. Clinical data and follow-up records were analyzed. Results Biochemical indicators significantly improved after treatment ,and the difference was statistically signifi-cant(P < 0.05). Fifty-six patients achieved complete remission,and 21 patients achieved partial remission,with an effective percentage of 75.5%,and adverse drug reactions incidence rate of 19.6%. There was not significant difference in the remission rate of different clinical types. Conclusions High dose of CTX shock treatment on children refractory nephrotic syndrome is effective ,with low adverse reactions incidence.
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Observational_studies
Idioma:
Zh
Revista:
The Journal of Practical Medicine
Año:
2017
Tipo del documento:
Article