Influence of Inhaled Corticosteroids on Airway Transforming Growth Factor - ?1 Expression of Asthmatic Remodeling Model / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)2003.
Article
en Zh
| WPRIM
| ID: wpr-638581
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the role of inhaled corticosteroids (ICS) on transforming growth factor - ?1 (TGF - ?1 )of asthmatic remodeling model Methods One hundred and eight guinea pigs were divided into 3 groups randomly and equally: asthmatic group( A), therapeutic group(B), control group(C) Three groups were treated by ovalbumin, budesonide, normal saline respectively The lung tissue specimens were collected after the guinea pigs were killed; the expression of TGF- ?1 was determined Results The expressions of TGF-?1 in A, K and C groups were(41 83 ? 10. 45) %, (27. 22 ? 8. 09)% , (15. 36 ? 2. 64)% respectively at 12 weeks. It was statistically significant( P
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
Journal of Applied Clinical Pediatrics
Año:
2003
Tipo del documento:
Article