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Progress on Nrf2 pathway in diabetic retinopathy / 中华实验眼科杂志
Article en Zh | WPRIM | ID: wpr-637677
Biblioteca responsable: WPRO
ABSTRACT
Diabetic retinopathy (DR) is a serious complication of diabetes mellitus,which leads to vision loss or even blindness.Nuclear factor erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor and plays an important role in oxidative stress and tissue injury associated with inflammation.More and more evidences show that Nrf2 play an important role in the onset and development of DR.This paper reviewed the role of Nrf2 pathway in diabetes mellitus and DR,and correlation between Nrf2 pathway and vascular endothelial growth factor (VEGF) expression.
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Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of Experimental Ophthalmology Año: 2016 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of Experimental Ophthalmology Año: 2016 Tipo del documento: Article